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Randomised, double-blind, placebo-controlled dose-escalation studies show that CJC-1295 produces sustained, dose-dependent increases in growth hormone and IGF-1, lasting several days after subcutaneous administration.[18] Ipamorelin has published human pharmacokinetic and pharmacodynamic data,[19] and has undergone a randomised phase-II study for postoperative ileus after bowel surgery.[20] But endocrine activity is not a dermatological outcome
doi: 10.4161/pri.4.2.11960 51 DisantoG.AdiutoriR.DobsonR.MartinelliV.Dalla CostaG.RuniaT.et al
In studies involving sciatic nerve transection, treatment with the peptide was linked to accelerated structural regeneration, characterized by improved organization of nerve bundles and increased presence of newly formed nerve fibers
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Tsivgoulis, G
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