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Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to [PMID: 10496977] Laboratory literature summary: Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones

An open-label placebo-controlled trial enrolled 77 people with elevated LDL cholesterol and triglycerides and randomized them into four groups: 1) placebo, 2) 10 mg or 20 mg daily of rosuvastatin, 3) bergamot polyphenols, and 4) bergamot polyphenols plus 10 mg rosuvastatin

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J Biotechnol (2021) 327:18

Then, seven shots are given on alternate days

Using Affymetrix microarray analysis on human fibroblast cultures, researchers documented that GHK-Cu at physiologically relevant concentrations (1-10 nM) significantly altered expression of 4,000+ genesapproximately 31.2% of all genes represented on the array