A 4mg (4,000mcg) dose = 4,000 / 5,000 x 100 = 80 units
In the general population, exposure to elevated levels of copper is usually through metal leeching from copper plumbing or copper lined cookware (2)
First things first, let's get your supplies in order
Because TBK1 is an essential autophagy-related protein which phosphorylate autophagy receptors (i.e., autophagic adaptor optineurin) to regulate the recruitment of cargo into autophagosomes (Weidberg and Elazar, 2011), it is possible that ICP34.5 could also indirectly inhibit autophagy by modulating TBK1 signaling
Additionally, crosstalk effect of different pathways in GGT and ChaC1/ChaC2 regulation requires further investigation
9b, quantification at the tumor: Fig