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Nonetheless, several groups should be considered at elevated risk and would generally be advised against use outside a controlled clinical trial
In summary, these data support a gut-joint axis in RA, which is based on zonulin-mediated impairment of intestinal barrier function and which is drugable by the zonulin antagonist larazotide
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-Vitamin B12: 2.4 mcg for adults
It was originally derived from a protective protein found in the human stomach
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