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It has been demonstrated that oxidative stress-mediated GSH depletion is crucial in controlling transient outward K+ currents in rat ventricular myocytes, which may be the cause of diabetes-related decreased contractility and aberrant electrical characteristics
Introduction Despite major advance in treatment, cardiovascular diseases are still one of the leading causes of mortality and morbidity in the world
Three months of trimetazidine (70 mg/day) in patients with cardiomyopathy decreased the myocardial -oxidation rate compared to placebo, implying its ability to shift mitochondrial processes to glucose oxidation [145]
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