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Association of gut microbiota-dependent metabolite trimethylamine N-oxide with first ischemic stroke

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However, this participant had a slower dose titration due to their heart failure, so took longer to reach the maximum dose

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5H, I), while overexpression of a codon-optimized L2HGDH (L2HGDH OPT ), which is resistant to the designed sgRNA, reverses this effect (Fig

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Small pilot studies have begun to explore this application more systematically

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