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Hwang, N.R., et al., Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions
Mol Cell 49 , 379387, doi:10.1016/j.molcel.2013.01.019 (2013)
Thus, activation of brain-derived GLP-1 would be necessary for peripherally circulating GLP-1/GLP-1RAs to engage GLP-1Rs in regions such as the ACB or VTA
2025;:10.1007/s40265-025-02263-0
Patients often experience decreased appetite, fewer cravings, increased energy, and marked improvements in vital health metrics, including blood pressure and cholesterol levels
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