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What makes this mechanism notable is its specificity
Furthermore, in rats, HSP70 has been shown not only to be necessary but sufficient to accelerate skin depigmentation.73 Finally, a study that introduced a mutant HSP70, in which only one amino acid was altered in its structure, showed that it was able to promote skin repigmentation by binding to dendritic cells and inactivating them and, consequently, inhibiting the subsequent T-cell response
Cell Host Microbe 33 , 941956.e910 (2025)
The keyword here is if
Through this interaction, TB-500 affects cytoskeletal organization and cellular motility pathways [4]
Baillieres Clin Haematol 8: 639-655
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