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Description

Indication and important safety information INCRELEX (mecasermin) is indicated for the treatment of growth failure in pediatric patients aged 2 years and older with severe primary IGF-1 deficiency* (IGFD), or with hormone (GH) gene deletion who have developed neutralizing antibodies to GH

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Rising intracellular calcium levels may drive the fusion of growth hormone-containing vesicles with the plasma membrane, facilitating the release of growth hormone into the extracellular environment

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Non-normalized data sets from selected results are shown in Supplementary Fig

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403: acute inhalation toxicity

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