Its not recommended for long-term use (typically limited to 3-4 month cycles), may cause irritation and contact dermatitis, and poses a risk of ochronosis (blue-black discoloration) with prolonged use, particularly in deeper skin tones
Given the vast amount of information on knock-off or compounded semaglutide being shared in the media, it is important for healthcare professionals and patients to have the clarity and confidence in knowing what they are using has undergone rigorous review for safety, effectiveness and quality
Unlike GLP-1, GIP suppresses glucagon secretion under hyperglycemic conditions
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Once the goal weight is achieved, they should increase their moderate aerobic exercise to 200 to 300 minutes a week for maintenance
Measured Growth-hormone release, alongside ACTH and cortisol - two stress-axis hormones that the earlier secretagogues tended to disturb