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In vitro barrier models using Caco-2 cells (gut epithelium) or brain endothelial cells could be employed to test the hypothesis that microbiota metabolites, such as butyrateeither administered directly or derived from patient-derived fecal microbiota culturescan strengthen epithelial and endothelial barrier function and reduce oxidative stress [40]
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Add Mushrooms A 2017 study found that mushrooms are the highest dietary source of glutathione and ergothioneine, two important antioxidants (2)
doi:10.1046/j.1365-2362.2001.00781.x
These outcomes align with the local effect theory
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