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Lancet (2019) 394(10192):3950
(The National Institutes of Health) Aging can make it more difficult for the body to break down and absorb B12
That stability profile is the main reason it appears so frequently in preclinical literature
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These hexapeptides showed appreciable GH-releasing potency but co-stimulated adrenocorticotropic hormone (ACTH), cortisol, and prolactin, a lack of selectivity that would become the central design problem for later compounds in the class
Access disparities exist, with studies suggesting lower utilization rates among Black, Hispanic, and other minority populations despite higher rates of diabetes and obesity in these communities
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