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AKT can also phosphorylate other chromatin-modifying enzymes, such as the histone methyltransferase EZH2 (H3K27 methylation) and DNA methyltransferase DNMT1, resulting in changes in function of these enzymes [90, 91]

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Implications of the DSIP-GILZ Connection: Stress Resilience: The GILZ protein is upregulated by dexamethasone (a potent corticosteroid) as a negative feedback mechanism to control inflammation

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