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Diabetic bone fragility through advanced glycation end product-collagen axis: Mechanisms and therapy of sodium glucose cotransporter 2 inhibitors Zhi-Peng Li, Cheng Luo, Xian-Mei Yu, Li-Ya Ye, Da Sun, Cheng-Zheng Duan, Shi-Yu Xu, Mei-Qi Zeng, Hui Xu, Zi-Yuan Peng, Peng Wang, Yao-Bin Wang, Wen-Jie Ruan, Meng-En Xue, Chang-Jiang Zhang, Dong-Juan He World Journal of Diabetes .2025;[Epub] CrossRef 8
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Antioxidants help stabilize free-radical molecules
Macrophage subsets (MAC.1, MAC.2) were distinguished by high expression of CD68, CEBPB , and FCER1G , while a third cluster (Inf.MAC) expressed NLRP3 and showed an inflammatory, cytokine-enriched, and pro-angiogenic profile with markers like IL1B and CCL3
The true magic is in choosing the right combination of workouts
173 This breakthrough highlights the importance of targeting inflammation as a therapeutic strategy for ASCVD
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