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Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing

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In preclinical research, AOD9604 is primarily investigated for its selective lipolytic activitythe ability to stimulate fat breakdown (lipolysis) and inhibit fat synthesis (lipogenesis) without exhibiting the growth-promoting or diabetogenic effects of full-length growth hormone