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Glutathione (GSH), the main intracellular antioxidant, increases upon amino acid (AA) administration in preterm infants, without an accompanying rise of the fractional synthesis rate of GSH (FSR GSH ) This study investigated the mechanism behind this increased GSH concentration by determining GSH synthesis in the first days after birth using stable isotope techniques in very low-birth-weight (VLBW) infants receiving i.v
Biometals 36, 263281
Reprod Biol 2005;5(1):5-17
Peptides enter circulation within 1530 minutes, producing a sharp plasma peak that research shows drops to sub-therapeutic levels within 3648 hours for small peptides under 2,000 daltons
However, the absence of Hippo signaling triggers unphosphorylated YAP/TAZ to translocate into the nucleus and activate mainly the transcriptional enhanced associate domain (TEAD) family of transcription factors to drive Hippo target gene expression in the liver
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