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For patients with type 2 diabetes and biopsy-proven NASH with fibrosis, pioglitazone may be considered under specialist supervision, as its use for liver disease is outside its licensed indication (type 2 diabetes) and requires careful assessment of potential risks and contraindications

The authors own conclusion was that short-term DSIP was not likely to be a major therapeutic benefit

Endocrinology 158 , 22552268 (2017)

This effect potentiated the proliferation-promoting actions of growth hormone through JAK2 pathway activation [6]

Fluctuations of intrinsically disordered, or unstable proteins generate heterogeneity (Nussinov et al