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For a 100 kg subject this back-calculates to about 100 mcg, which is likely why 100 mcg became the default modeling figure

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The same proglucagon gene is expressed in pancreatic alpha cells, but different enzymatic processing in those cells produces glucagon instead of GLP-1

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We found that the TAC-induced increase in free fatty acids led to myocardial lipid accumulation, while myocardial lipid accumulation was significantly decreased after Sema treatment (Fig