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Pen-injector specifics: Once you puncture a cartridge with a pen needle, most manufacturers rate the in-use shelf life at 28 days at 2 to 8 C
This escalation is intentional
The drug is injected sterile IM/SQ
In severe cases, an abscess can form requiring incision and drainage
From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models
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