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Fouque D, Holt S, Guebre-Egziabher F, Nakamura K, Vianey-Saban C, Hadj-Aissa A, et al
Research has demonstrated that PINK1 is an upstream regulator of Parkin, with both proteins synergistically mediating the polyubiquitination of structural or functional proteins on the surface of damaged mitochondria, playing a pivotal role in the autophagic degradation of depolarized mitochondria [26]
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Dont keep a restrictive diet for too long
In controlled laboratory research environments, NNMT activity is associated with nicotinamide metabolism, cellular energy balance, and biochemical signaling networks
