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All except one of the six genetic studies considered Hardy Weinberg equilibrium [47, 50, 94, 96, 97], two provided power calculations [96, 97] and two adjusted for multiple comparisons [50, 97] (although a footnote indicating that the associations were no longer statistically significant was not added in one case) [50]

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C.AgarwalR.et al (2020)

HbA1C reductions ranged from 1.2% to 1.8% depending on dose and baseline glycemia

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During the time frame of the study, mice did not exhibit any overt short-term negative health impacts from the shrunken muscle