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APAP overdose leads to the increasing expression of IL-33[74], CXCL (CXC Motif Chemokine Ligand)1 [75], CXCL2 [76] and other pro-inflammatory factors, finally resulting in more neutrophils activation and recruitment

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At nighttime, lixisenatide increased HR by 2.2 bpm compared with approximately 10 bpm for both liraglutide doses (Table 1)

It is well-tolerated with essentially no side effects, making it an attractive option for patients who prefer non-pharmacological approaches