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Loperamide (Imodium, among others) is another antidiarrheal agent that interacts with opioid receptors to inhibit peristalsis and increase transit time

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Astrocytes release free fatty acids (FFAs) from lipid droplets, and the released fatty acids enter the mitochondria and bind to carnitine to form LCACs, the accumulation of which leads to mitochondrial dysfunction in astrocytes and exacerbates neuronal damage [115]

The timeline for side effects typically follows a predictable pattern, peaking early and fading

(2024) Glucagon-like peptide 1 receptor agonist use and risk of thyroid cancer: Scandinavian cohort study