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Preclinical studies in diet-induced obese mice have examined its effects on adipose tissue and glucose tolerance
What Research Shows (Up to 12 Weeks): Chronic toxicity : None documented (studies up to 12 weeks) Organ damage : None detected in histopathological examination Carcinogenic effects : None observed (though dedicated cancer studies haven't been done) Reproductive toxicity : None found in limited fertility studies What We Don't Know: 1
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J.Cancer 90 , 10841092 (2004)
Grouping: Young control group, elderly control group, AOD 9604 group (500 g/kg/day), positive drug group (alendronate sodium, 10mg/kg/week)
Wang D, et al
However, some clinics offering the retatrutide-cagrilintide combination use a ratio of approximately 5:1 (retatrutide to cagrilintide), which at a retatrutide dose of 10-12 mg would put cagrilintide at 2.0-2.5 mg
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