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"Drug Approval Package: Janumet XR (sitagliptin/metformin hydrochloride) NDA #202270"
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Obesity Obesity is the primary indicator of modern incretin-based therapies, particularly because of their ability to target central appetite regulation, GI motility, and peripheral metabolic processes
Jumping to the full dose immediately would produce severe nausea and vomiting in most people
Contact your healthcare provider for any new intermenstrual bleeding, postmenopausal bleeding, heavy bleeding soaking through pads hourly, bleeding with severe pain or dizziness, or spotting that persists beyond two to three cycles
doi:10.1056/NEJMoa1501352 Rosenstock J, Perkovic V, Johansen OE, et al
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