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Gastrointestinal effects of GLP-1 receptor agonists: From basic science to clinical relevance
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GLP-1 (Glucagon-Like Peptide-1) is a hormone naturally produced in the body
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Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
Side Effects Like Nausea: GLP-1 RAs commonly cause gastrointestinal side effects such as nausea, vomiting, or a feeling of fullness in the stomach
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