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Stimulation of GLP-1R with peptide and small molecule agonists results in selective subcellular activation Building on these observations, we wondered if endosome-to-Golgi retrograde transport was a common mechanism for peptide and small molecule GLP-1R agonists

"Our study highlights several biological pathways by which GLP1 drugs may influence Alzheimer's, including reducing inflammation, improving insulin signaling in the brain, and altering enzymes involved in the production of amyloidbeta." GLP-1 drugs get their name from the glucagon-like peptide-1 (GLP-1) hormone that they mimic

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