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& Chaves, V
Animal studies suggest a high safety margin
If the patient experiences gastrointestinal adverse effects during dose escalation, uptitration can be delayed for an additional week [21]
FNDC5, fibronectin type III domain-containing protein 5
Background Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are an important advancement in treating obesity and type 2 diabetes as they increase insulin secretion after meals without triggering hypoglycemia, helping reduce appetite and consequently body weight
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