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Taurine conjugation of bile acids is essential for proper biliary excretion of large, lipophilic toxins that have been glucuronidated or glutathione-conjugated
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The study involved 411 adult patients with T2DM and was designed as a randomized, double-blind, placebo-controlled trial where patients received varying doses of danuglipron or a placebo
These results are comparable to the weight loss seen in clinical trials
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By reducing the degree of obesity and improving cardiometabolic health irrespective of prior response to childhood obesity care, GLP-1 based treatment could help more young people with severe obesity to reduce their burden of obesity-related complications in early adulthood, said study author Joachim Holt from the University of Copenhagen, in a press release
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