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These effects are typically dose-related and diminish over the first 4-8 weeks of treatment
Although there is no clinical trial evidence supporting use of GLP-1 RAs and tirzepatide specifically in this group, they were recommended to reduce the very high lifetime risk of cardiovascular complications
BMJ Open 2021;11:e051506 19
4 It also modulates inflammation by affecting cytokine production and supports immune function through the regulation of white blood cells
Mioduchoski, FNP-BC Patients sometimes become discouraged if dramatic changes are not visible during the first month
( f ) t(13)=0.997, p = 0.337
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