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Trial SOUL (McGuire et al., NEJM 2025) Design Phase 3 / event-driven Population Adults with T2D + ASCVD or CKD Key result Oral semaglutide significantly reduced MACE vs placebo in high-CV-risk T2D
Breneman JC
Applying a cold pack or pain relief medication recommended by your dermatologist can help reduce discomfort
The PP analysis set comprised all patients in the FAS who have not violated any inclusion criteria, have not fulfilled any exclusion criteria, have a valid baseline A1C measurement and were exposed to treatment and have at least 1 valid A1C measurement while on treatment without rescue medication at or after week 14
Current formulations of GLP-1 analogs rely primarily on subcutaneous injections, which may pose challenges to patient convenience and long-term adherence
Store dry vials in a cool, dry place
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