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NAC takes the lead here because it's more versatile and bioavailable
If you are deficient in vitamin B12, then the hydroxocobalamin B12 shots are very effective at raising your blood levels or preventing a deficiency
Two other surrogate markers of B12 deficiency are elevated homocysteine and MCV, although several other nutrient deficiencies can cause these levels to be elevated, so be sure to work with your provider when interpreting any lab test results
Annu Rev Neurosci 25:103126 Mariga A, Zavadil J, Ginsberg SD, Chao MV (2015) Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function
Intramuscular B12 injections produce faster results than oral supplementation, with reticulocytosis typically beginning by day 34 of treatment