For others, it can take a few weeks to notice big changes
Also, high-dose B12 has been linked to acneiform eruptions in some case reports and reviews (Bahbouhi et al., 2023) as described in the PubMed record
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This could theoretically affect DNA methylation, gene expression, and other processes dependent on methylation
Actual medications may vary depending on the prescribing provider, pharmacy, and applicable regulations
No dose-ranging study has established a human oral dose for this compound, so the high oral numbers circulate as community and vendor convention rather than as published clinical figures