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Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies

For patients with severe deficiency or conditions such as pernicious anemia, our team may recommend an initial loading phase, which often involves administering 1000 mcg of B12 intramuscularly or subcutaneously daily or every other day for one to two weeks

42 Quantification of 8-oxo-dG in DNA was performed using mass spectrometry/liquid chromatography on a LCQ Advantage MAX system (Thermo Electron Corporation, Waltham, MA, USA) and expressed as pmol per mg DNA

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