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Old matrix components are degraded, new proteins are synthesized, and cellular populations reorganize in response to changing physiological demands
Sterile water lacks preservatives and must be used immediately after reconstitution
Modeling colorectal cancer progression reveals niche-dependent clonal selection
Extensive pre-clinic studies and clinical trials also are required for proving the druggable potential of these targets
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Plain sterile water can be used but limits shelf life to 24 hours
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