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[1] [2] This occurs because B12 deficiency commonly affects the peripheral nerves, particularly those extending to the extremities

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Elderly patients may be more sensitive to the medications effects and may require slower titration or lower maintenance doses, particularly if they have reduced renal function or are at higher risk for dehydration from gastrointestinal adverse effects

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Vitamin B12 deficiency often leads to nervous system damage that damages the optic nerve leading to your eyes