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Simultaneously, GHK-Cu appears to support matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), suggesting it might regulate both synthesis and degradation of ECM componentsan important attribute for dynamic tissue remodeling
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Representative tissue specimens were embedded in paraffin, sectioned at 4 m, stained with hematoxylin and eosin (H&E), and evaluated by light microscopy using an Olympus 71 digital camera and an Olympus BX51 microscope (Japan) acquiring digital images saved as uncompressed 24-bit RGB TIFF files
J Cell Biol 169:2934
10% of participants on placebo) 39
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