Retatrutide (LY3437943) is a first-in-class triple-receptor agonist peptide developed by Eli Lilly that simultaneously activates three metabolic receptors: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon
Patients should also contact their GP or diabetes specialist nurse if they experience persistent gastrointestinal symptoms leading to inadequate fluid intake, as dehydration can affect cardiovascular function
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