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In biochemical and cellular research systems, L-glutathione is widely used as a reference compound for studying oxidative stress, redox signalling, enzymatic detoxification pathways, and glutathione-dependent enzyme activity

Aside from inducing fat deposition to cause inflammation in TME, macrophages living in the TME are also the target of insulin

However, excessive mitophagy induces cell death (Shi et al., 2014)

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Reactive oxygen intermediates as mediators of programmed cell death in plants and animals