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Tesamorelin stimulates pituitary GH release via the GHRH receptor while ipamorelin stimulates the same cells via the GHS-R1a (ghrelin) receptor
doi: 10.1016/j.molmet.2019.09.010 42 AndrikouETsioufisCAndrikouILeontsinisITousoulisDPapanasN
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While direct mutagenic effects were not identified in safety studies, proliferative effects were, representing a plausible pathway for increased risk of PDAC
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