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La precocidad de la separacin de las curvas de aparicin de MACE entre los brazos de SEMA y placebo23 sugiere una potencial participacin directa de SEMA en los resultados del estudio SELECT, a travs de efectos promotores de angiognesis y reduccin de estrs oxidativo e inflamacin, en el contexto de acciones antiaterognicas derivadas de la activacin del GLP-1R que favorecen la funcin endotelial y la supervivencia celular7 (fig
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This improves their quality of life
Kim EH, Surh YJ (2008) The role of 15-deoxy-12,14-prostaglandin J2, an endogenous ligand of peroxisome proliferator-activated receptor , in tumor angiogenesis
