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Patients on semaglutide often find that they naturally eat 3050 percent fewer calories per day without actively counting or restricting food

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Because tirzepatide's half-life is 5 days, missing one weekly injection means you'll have about 50% of the previous dose still circulating after 7 days

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This work has been widely read as evidence that neuroinflammation is a driver of neurodegeneration rather than merely a downstream marker, although that interpretation remains the subject of active investigation