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Dosing tiers: Splitting the dose into two administrations (AM and PM) maintains more consistent lipolytic signaling across a 24-hour period

This makes it significantly more practical than single-use sterile water for research protocols that involve repeated compound preparation over days or weeks

This response was more limited to the gut, so may have helped more in people with gastrointestinal issues like irritable bowel syndrome and Crohns

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These are cautious recommendations because data are sparse