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[] The neurobiological mechanisms associated with schizophrenia include abnormalities in glutamatergic neurotransmission, indicated by decreased concentrations of glutamate in the brain and receptor NMDA malfunction

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Both tirzepatide and retatrutide use gradual titration, but the specifics differ in ways that affect real-world outcomes

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A medical provider can help determine if a patient would benefit from these other medications and discuss risks versus benefits with the patient

The findings were published in T he Journal of Clinical Endocrinology & Metabolism