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In the last four decades, the discovery and development of glucagon-like peptide 1 receptor agonists (GLP- 1RAs) reshaped the landscape of diabetes and weight management

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GLP-1 receptor agonists as a class share similar mechanisms and therefore comparable digestive effects, though individual medications show some distinctions

This work was partially supported by the Ministry of Science and Technology (China) grants (2018YFA0507002 to H.E.X.)