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It signals the somatotroph cells of the anterior pituitary to secrete GH that is already synthesized and stored
Several studies have explored its potential influence on angiogenesis pathways, nitric oxide signaling, and mechanisms involved in wound healing
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Comparison with the binding modes of other dual and triple agonists highlight that the N-terminal and C-terminal regions of the peptide confer receptor selectivity, whereas the middle region offers opportunities for sequence optimization to refine receptor engagement, thereby presenting a useful template for designing better unimolecular therapeutics
Intestinal sensing by gut microbiota: targeting gut peptides
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