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Specifically, genes related to lipid storage (CD36 molecule ( Cd36 ), sterol regulatory element binding protein ( Srebp )) and adipocyte differentiation (peroxisome proliferator activated receptor gamma ( Pparg )) are significantly downregulated with reduced CNS GIPR signalling 46
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Diseases such as Alzheimers, dementia, sarcopenia, arthritis, Parkinsons, osteoporosis, maculopathy, COPD, and cancer increase with advancing age (Franceschi et al 2018)
Additional resources include a podcast (22 episodes covering topics from GLP-1 medications to cravings and self-sabotage), weekly live webinars, and exercise videos
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