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Vitamin B-12 plays a crucial role in the production of red blood cells and the conversion of food into energy
Treatment considerations include: Concurrent folate supplementation if deficient (never give folate alone, as it may precipitate neurological deterioration) Potassium monitoring during initial treatment in severe anaemia or at-risk patients (e.g., those with heart failure) Response assessment: reticulocyte count peaks at 57 days, haemoglobin normalises within 68 weeks Neurological symptoms may take 612 months to improve and may not fully resolve Patients should be advised that treatment for pernicious anaemia or post-surgical deficiency is lifelong
Making injectable B12 OTC from pharmacies would profoundly change lives for the better
Liver disease is a significant cause of elevated B12
March 24, 2023
