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What that wisdom missed - and what a small group of academic endocrinologists, most prominently Richard DiMarchi's group at Indiana University, had begun to argue aggressively through the early 2010s - was that glucagon's metabolic role is not just "raise glucose." It is a broader lever on hepatic lipid handling, mitochondrial uncoupling, brown-fat activation, and energy expenditure

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Apigenin inhibits the growth of ER-positive breast cancer cells via its action as an oestrogen receptor antagonist and its potential regulation of the AKT/FOXM1 pathway (163)

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