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These challenges are primed to look chemically and procedurally like what the field has previously seen in oncology around the CDK4/6 cluster (palbociclib, ribociclib, abemaciclib) and in the SGLT2 inhibitor space

This result indicates that GSH concentration is likely dependent on acidity and that its acidity plays a significant role in its biofilm disruption activity

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Reduced shedding becomes consistent

V.et al (2018)

doi:10.1210/clinem/dgaa327 59